Paul Goldschmidt, when he wasn't making sure that your engagement ring is so perfectly suited to your individual tastes that you'll never want to take it off, took enough time off to lead the NL in HRs, SlgPct, and OPS in 2013 while manning 1B for the DBAcks and finishing 2nd in MVP to Andrew McCutcheon. He already has 9 XBHs so far this year and, IIRC, fields and runs fairly well too. He also, as far as I know, has never contracted Valley Fever (or even Johnny Fever) despite living in Arizona and occasionally visiting Cincinnati.